|By PR Newswire||
|February 27, 2013 12:00 PM EST||
— $53 million matched, positioning Foundation for continued impact; opportunity and need persist in challenged research funding environment —
NEW YORK, Feb. 27, 2013 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation for Parkinson's Research (MJFF) announced that with the help of the Parkinson's community, it has completed and surpassed the $50-million Brin Wojcicki Challenge. Longtime Foundation supporters Sergey Brin and Anne Wojcicki have matched more than $53 million in capacity-building gifts received by MJFF from January 1, 2011, to December 31, 2012.
Mr. Brin and Ms. Wojcicki, the Foundation's largest donors for several years running, spearheaded the Challenge to spur donors at every level to give, renew or increase giving to MJFF. Because of the enthusiasm and generosity of the Foundation's community of donors, Challenge-eligible giving exceeded the original goal by about $3 million — additional dollars that Mr. Brin and Ms. Wojcicki have agreed to match.
"Anne and Sergey's friendship to our Foundation and to Parkinson's patients worldwide is awe-inspiring," said Michael J. Fox. "As if a $50-million match weren't tremendous in its own right, they've gone above and beyond their initial commitment to match the $3 million extra ponied up by our incredible supporters. There's no doubt the Challenge has made our community stronger and more vibrant in its passionate pursuit of a cure."
Over the course of two years, the Challenge brought thousands of new contributors to MJFF. It also helped the Foundation reactivate relationships with thousands of supporters who had given prior to 2010, and motivated over 4,000 to stretch their giving in order to double the impact of their generosity.
Mr. Brin is co-founder of Google. Ms. Wojcicki is co-founder of 23andMe, a personal genetics company. With the completion of the Challenge, their personal giving to MJFF totals more than $157.5 million since 2004.
An opportune moment and an urgent need
Mr. Brin and Ms. Wojcicki chose an opportune moment in Parkinson's drug development to launch the Challenge. MJFF and most of its research partners believe that the pipeline of new Parkinson's treatments is as robust as it has been in decades, if not ever. Understanding of the factors underlying disease onset and progression is increasing, and insights from genetics are opening new avenues for therapeutic development. In the midst of this promising activity, government and commercial sources of research funding continue to dry up. Especially as more research approaches the clinic, where costs rise steeply, there has never been a more important time or a greater need for the Parkinson's community to work together to ensure funding sufficient to keep the most promising projects moving forward.
At the outset of 2013, MJFF remains focused on:
- The search for a disease-modifying treatment. This spring, results are expected from Ceregene, Inc.'s most recent MJFF-supported Phase 2 clinical trial of neurturin, a trophic factor that could help restore dopamine neurons in the Parkinson's brain. As Parkinson's genetics continues to revolutionize the field, MJFF is growing its initiatives focused on alpha-synuclein and LRRK2, the two most important genetic targets in PD. And in coming months the Foundation's landmark biomarker study, Parkinson's Progression Markers Initiative (ppmi-info.org), will complete collection of baseline data (all of which has been made available to the research community at large in real time) and launch a new arm to study people at increased risk for the disease.
- Looking beyond the dopamine system. Today researchers understand that Parkinson's involves a constellation of symptoms that go well beyond dopamine signaling. MJFF-enabled partnerships with Bristol Myers Squibb, Sanofi, Addex and other major pharmaceutical firms are pushing new classes of symptomatic therapies, as well as treatments for cognition and dyskinesia, closer than ever to the clinic.
- Increasing the flow of willing volunteers for clinical research through Fox Trial Finder. Fox Trial Finder (foxtrialfinder.org) has registered more than 14,000 patient and control volunteers who want to be matched to the best trials for them. In 2013 the site comes online in five more European countries and aims to attain 30,000 registered volunteers by year-end.
"Our Foundation's promise to Parkinson's patients is to work urgently to identify and fund the projects closest or most critical to practical therapeutic relevance," said Todd Sherer, Ph.D., CEO of MJFF. "We're grateful to our Challenge participants and our entire community of supporters for helping us continue to fulfill that promise."
About The Michael J. Fox Foundation for Parkinson's Research
As the world's largest private funder of Parkinson's research, The Michael J. Fox Foundation is dedicated to accelerating a cure for Parkinson's disease and improved therapies for those living with the condition today. The Foundation pursues its goals through an aggressively funded, highly targeted research program coupled with active global engagement of scientists, Parkinson's patients, business leaders, clinical trial participants, donors and volunteers. In addition to funding more than $300 million in research to date, the Foundation has fundamentally altered the trajectory of progress toward a cure. Operating at the hub of worldwide Parkinson's research, the Foundation forges groundbreaking collaborations with industry leaders, academic scientists and government research funders; increases the flow of participants into Parkinson's disease clinical trials with its online tool, Fox Trial Finder; promotes Parkinson's awareness through high-profile advocacy, events and outreach; and coordinates the grassroots involvement of thousands of Team Fox members around the world.
SOURCE The Michael J. Fox Foundation for Parkinson's Research
When it comes to the Internet of Things, hooking up will get you only so far. If you want customers to commit, you need to go beyond simply connecting products. You need to use the devices themselves to transform how you engage with every customer and how you manage the entire product lifecycle. In his session at @ThingsExpo, Sean Lorenz, Technical Product Manager for Xively at LogMeIn, will show how “product relationship management” can help you leverage your connected devices and the data they generate about customer usage and product performance to deliver extremely compelling and reliabl...
Feb. 27, 2015 08:15 AM EST Reads: 374
One of the biggest impacts of the Internet of Things is and will continue to be on data; specifically data volume, management and usage. Companies are scrambling to adapt to this new and unpredictable data reality with legacy infrastructure that cannot handle the speed and volume of data. In his session at @ThingsExpo, Don DeLoach, CEO and president of Infobright, will discuss how companies need to rethink their data infrastructure to participate in the IoT, including: Data storage: Understanding the kinds of data: structured, unstructured, big/small? Analytics: What kinds and how responsiv...
Feb. 27, 2015 05:00 AM EST Reads: 2,135
Since 2008 and for the first time in history, more than half of humans live in urban areas, urging cities to become “smart.” Today, cities can leverage the wide availability of smartphones combined with new technologies such as Beacons or NFC to connect their urban furniture and environment to create citizen-first services that improve transportation, way-finding and information delivery. In her session at @ThingsExpo, Laetitia Gazel-Anthoine, CEO of Connecthings, will focus on successful use cases.
Feb. 27, 2015 04:00 AM EST Reads: 2,789
Cloudian, Inc., the leading provider of hybrid cloud storage solutions, today announced availability of Cloudian HyperStore 5.1 software. HyperStore 5.1 is an enhanced Amazon S3-compliant, plug-and-play hybrid cloud software solution that now features full Apache Hadoop integration. Enterprises can now transform big data into smart data by running Hadoop analytics on HyperStore software and appliances. This in-place analytics, with no need to offload data to other systems for Hadoop analyses, enables customers to derive meaningful business intelligence from their data quickly, efficiently and ...
Feb. 27, 2015 04:00 AM EST Reads: 2,275
Sensor-enabled things are becoming more commonplace, precursors to a larger and more complex framework that most consider the ultimate promise of the IoT: things connecting, interacting, sharing, storing, and over time perhaps learning and predicting based on habits, behaviors, location, preferences, purchases and more. In his session at @ThingsExpo, Tom Wesselman, Director of Communications Ecosystem Architecture at Plantronics, will examine the still nascent IoT as it is coalescing, including what it is today, what it might ultimately be, the role of wearable tech, and technology gaps stil...
Feb. 27, 2015 03:30 AM EST Reads: 2,232
The true value of the Internet of Things (IoT) lies not just in the data, but through the services that protect the data, perform the analysis and present findings in a usable way. With many IoT elements rooted in traditional IT components, Big Data and IoT isn’t just a play for enterprise. In fact, the IoT presents SMBs with the prospect of launching entirely new activities and exploring innovative areas. CompTIA research identifies several areas where IoT is expected to have the greatest impact.
Feb. 27, 2015 02:00 AM EST Reads: 2,926
Wearable devices have come of age. The primary applications of wearables so far have been "the Quantified Self" or the tracking of one's fitness and health status. We propose the evolution of wearables into social and emotional communication devices. Our BE(tm) sensor uses light to visualize the skin conductance response. Our sensors are very inexpensive and can be massively distributed to audiences or groups of any size, in order to gauge reactions to performances, video, or any kind of presentation. In her session at @ThingsExpo, Jocelyn Scheirer, CEO & Founder of Bionolux, will discuss ho...
Feb. 27, 2015 12:00 AM EST Reads: 2,816
The explosion of connected devices / sensors is creating an ever-expanding set of new and valuable data. In parallel the emerging capability of Big Data technologies to store, access, analyze, and react to this data is producing changes in business models under the umbrella of the Internet of Things (IoT). In particular within the Insurance industry, IoT appears positioned to enable deep changes by altering relationships between insurers, distributors, and the insured. In his session at @ThingsExpo, Michael Sick, a Senior Manager and Big Data Architect within Ernst and Young's Financial Servi...
Feb. 26, 2015 11:00 PM EST Reads: 947
The Internet of Everything (IoE) brings together people, process, data and things to make networked connections more relevant and valuable than ever before – transforming information into knowledge and knowledge into wisdom. IoE creates new capabilities, richer experiences, and unprecedented opportunities to improve business and government operations, decision making and mission support capabilities. In his session at @ThingsExpo, Gary Hall, Chief Technology Officer, Federal Defense at Cisco Systems, will break down the core capabilities of IoT in multiple settings and expand upon IoE for bo...
Feb. 26, 2015 10:30 PM EST Reads: 934
SYS-CON Events announced today that Vitria Technology, Inc. will exhibit at SYS-CON’s @ThingsExpo, which will take place on June 9-11, 2015, at the Javits Center in New York City, NY. Vitria will showcase the company’s new IoT Analytics Platform through live demonstrations at booth #330. Vitria’s IoT Analytics Platform, fully integrated and powered by an operational intelligence engine, enables customers to rapidly build and operationalize advanced analytics to deliver timely business outcomes for use cases across the industrial, enterprise, and consumer segments.
Feb. 26, 2015 09:45 PM EST Reads: 906
The Internet of Things (IoT) is causing data centers to become radically decentralized and atomized within a new paradigm known as “fog computing.” To support IoT applications, such as connected cars and smart grids, data centers' core functions will be decentralized out to the network's edges and endpoints (aka “fogs”). As this trend takes hold, Big Data analytics platforms will focus on high-volume log analysis (aka “logs”) and rely heavily on cognitive-computing algorithms (aka “cogs”) to make sense of it all.
Feb. 26, 2015 07:00 PM EST Reads: 852
SYS-CON Events announced today that GENBAND, a leading developer of real time communications software solutions, has been named “Silver Sponsor” of SYS-CON's WebRTC Summit, which will take place on June 9-11, 2015, at the Javits Center in New York City, NY. The GENBAND team will be on hand to demonstrate their newest product, Kandy. Kandy is a communications Platform-as-a-Service (PaaS) that enables companies to seamlessly integrate more human communications into their Web and mobile applications - creating more engaging experiences for their customers and boosting collaboration and productiv...
Feb. 26, 2015 05:00 PM EST Reads: 1,161
From telemedicine to smart cars, digital homes and industrial monitoring, the explosive growth of IoT has created exciting new business opportunities for real time calls and messaging. In his session at @ThingsExpo, Ivelin Ivanov, CEO and Co-Founder of Telestax, shared some of the new revenue sources that IoT created for Restcomm – the open source telephony platform from Telestax. Ivelin Ivanov is a technology entrepreneur who founded Mobicents, an Open Source VoIP Platform, to help create, deploy, and manage applications integrating voice, video and data. He is the co-founder of TeleStax, a...
Feb. 26, 2015 03:30 PM EST Reads: 3,866
The industrial software market has treated data with the mentality of “collect everything now, worry about how to use it later.” We now find ourselves buried in data, with the pervasive connectivity of the (Industrial) Internet of Things only piling on more numbers. There’s too much data and not enough information. In his session at @ThingsExpo, Bob Gates, Global Marketing Director, GE’s Intelligent Platforms business, to discuss how realizing the power of IoT, software developers are now focused on understanding how industrial data can create intelligence for industrial operations. Imagine ...
Feb. 26, 2015 03:15 PM EST Reads: 1,074
Feb. 26, 2015 02:30 PM EST Reads: 2,257
The 3rd International @ThingsExpo, co-located with the 16th International Cloud Expo - to be held June 9-11, 2015, at the Javits Center in New York City, NY - is now accepting submissions to demo smart cars on the Expo Floor. Smart car sponsorship benefits include general brand exposure and increasing engagement with the developer ecosystem.
Feb. 26, 2015 02:00 PM EST Reads: 1,596
Operational Hadoop and the Lambda Architecture for Streaming Data Apache Hadoop is emerging as a distributed platform for handling large and fast incoming streams of data. Predictive maintenance, supply chain optimization, and Internet-of-Things analysis are examples where Hadoop provides the scalable storage, processing, and analytics platform to gain meaningful insights from granular data that is typically only valuable from a large-scale, aggregate view. One architecture useful for capturing and analyzing streaming data is the Lambda Architecture, representing a model of how to analyze rea...
Feb. 26, 2015 02:00 PM EST Reads: 1,068
Feb. 26, 2015 12:45 PM EST Reads: 539
SYS-CON Events announced today that Open Data Centers (ODC), a carrier-neutral colocation provider, will exhibit at SYS-CON's 16th International Cloud Expo®, which will take place June 9-11, 2015, at the Javits Center in New York City, NY. Open Data Centers is a carrier-neutral data center operator in New Jersey and New York City offering alternative connectivity options for carriers, service providers and enterprise customers.
Feb. 26, 2015 12:00 PM EST Reads: 1,720
Feb. 26, 2015 12:00 PM EST Reads: 1,129